DIFFERENCIAL IMMUNOKORRECTION IN WOMEN WITH GENITAL ENDOMETRIOSIS

DIFFERENCIAL IMMUNOKORRECTION IN WOMEN WITH GENITAL ENDOMETRIOSIS

Authors

  • Ismoilova Dildora Urgench branch of TMA, Republican Scientific Center of Immunology MH RUz, 2-TMA.
  • Musokhodjaeva Dilorom Urgench branch of TMA, Republican Scientific Center of Immunology MH RUz, 2-TMA.
  • Magzumova Nargiza. Urgench branch of TMA, Republican Scientific Center of Immunology MH RUz, 2-TMA.

Keywords:

genital external and internal endometriosis, immune status, phagocytosis, cytokines.

Abstract

56 patients with genital endometriosis were examined. Of these, 26 had internal endometriosis, and 30 had external genital endometriosis. 18 practically healthy women made up a control group. All examined women were examined the state of the immune system (cellular immunity, phagocytosis and cytokine status). It was found that in patients with endometriosis, the level of T-lymphocytes and its subpopulation composition were reduced, and the level of killer activity varied in different ways depending on the form of genital endometriosis. Functional activity of neutrophils changed only in the group of women with EGE.

References

Selkov S.A., Yarmolinskaya M.I., Pavlov O.V. i dr. Sistemniie I lokalnie urovni regulyasii immunopatogenicheskix prosessov u pasientok s narujnim genitalnim endometriozom.//Jurn.akush.i jen. bol. - 2005. - T. LIV, NO. 1. - pp. 20-28.

Solodovnikova N.G., Niauri D.A. Rol faktorov immunnoy sistemi v patogeneze narujnova genitalnogo endometrioza. //Beul. Federalnogo sentra serdsa, krovi i endokrinologii im. V.D. Almazova. - 2011. - №6. - S. 23-28.

Shishkov D.N. Rol immunnix narushenie v razvitii besplodiya pri malix formax narujnogo genitalnogo endometrioza: Avtoref. dis. ...kand. med. Nauk. -Ivanovo, 2007.

Bohler, N.S. et al. Endometriosis markers: immu¬nologic alterations as diagnostic indicators for en¬dometriosis (in Russian) // Reprod. Sci. - 2007. - Vol. 14, №6. -

P. 595-604.

Burney R.O. The genetics and biochemistry of en¬dometriosis // Curr. Opin. Obstet. Gynecol. - 2013. -Vol. 25.-P. 280-286. *

Podgaec S. et al. Endometriosis: an inflammatory disease with a Th2 immune response component // Human Reproduction. - 2007. - Vol. 22, №5. - P. 1373-1379. Buyanova S.N., Shchukina N.A., Gorshilin A.V. Reproductive prognosis in patients with purulent inflammatory diseases of small pelvis: problems and solutions. Russian messenger of obstetrician-gynecologist. 2009; 2: 65-68.

Zubkov M.N. Collection, transportation of biological material and interpretation of microbiological research results. Clinical microbiology and antibacterial chemotherapy. 2004; 6; 2: 143-154.

Kisina V.I., Kanishcheva E.Yu., Dmitriev G.A., Yakovlev V.P. Clinical, microbiological and morphological features of chronic inflammatory diseases of small pelvis organs in women. Sexually transmitted infections. 2002; 2: 10-14.

Identifier of Bergie bacteria. Edited by Hoult J., Krieg N., Sneeta P., Steely J., Williams S. Moscow: "Mir". 1997; Т.1-2.

Ross J.D.S. European guidelines for inflammatory diseases of the pelvic organs and perihepatitis // Sexually transmitted infections. 2002; 2: 34-37.

Utkin, E.V.; Kulavskiy, V.A. Main reasons of development and modern tendencies in the clinical course of the inflammatory diseases of the pelvic organs in women. Russian messenger of obstetrician-gynecologist. 2008; 1: 40-44.

Yaglov V.V. Inflammatory diseases of the pelvic organs. Gynecology. 2006; 4: 46-47.

Bohm M.K., Newman L., Satterwhite C.L., Tao G., Weinstock H.S. Pelvic inflammatory disease among privately insured women, United States, 2001-2005. Sex Transm Dis. 2010; 37(3): 131-136.

Abatangelo L., Okereke L., Parham-Foster C., Parrish C., Scaglione L., Zotte D., Taub L.F. If pelvic inflammatory disease is suspected empiric treatment should be initiated. J Am Acad Nurse Pract. 2010; 22(2): 117-122.

Yaglov V.V., Prilepskaya V.N. Inflammatory diseases of the pelvic organs in the practice of a gynecologist // Gynecology. - Moscow, 2007. - №3. - C.18-21.

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Published

2024-06-01

How to Cite

Ismoilova Dildora, Musokhodjaeva Dilorom, & Magzumova Nargiza. (2024). DIFFERENCIAL IMMUNOKORRECTION IN WOMEN WITH GENITAL ENDOMETRIOSIS. IMRAS, 7(6), 440–445. Retrieved from https://journal.imras.org/index.php/sps/article/view/1574

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