POLYCYSTIC OVARY SYNDROME IN CHILDBEARING WOMEN IN ANDIJAN: A CLINICAL, BIOCHEMICAL, AND HORMONAL ASSESSMENT

POLYCYSTIC OVARY SYNDROME IN CHILDBEARING WOMEN IN ANDIJAN: A CLINICAL, BIOCHEMICAL, AND HORMONAL ASSESSMENT

Authors

  • Kholmatova Gulhayo Azimovna Ph.D., Associate Professor
  • Razakova Shokhsanam Tulkinovna Assistant
  • Ibragimova Dilhumor Dilshodbekovna Master's Degree, 2nd year Endocrinology specialty Department of Hospital Therapy and Endocrinology Andijan State Medical Institute
  • Khafizova Rufina Radikovna Chemotherapist Department of Oncology Republican Specialized Scientific and Practical Center of Oncology and Radiology Andijan Branch

Keywords:

Polycystic Ovary Syndrome, Childbearing Women, Andijan, Clinical Assessment, Biochemical Profiles, Hormonal Imbalance.

Abstract

Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder affecting women of childbearing age, with implications for reproductive, metabolic, and psychological health. This study assesses childbearing women's clinical, biochemical, and hormonal profiles in Andijan, Uzbekistan. 200 women were randomly selected from the population for clinical evaluation, biochemical testing, and hormonal assays. Key findings include a high prevalence of insulin resistance, hyperandrogenism, and abnormal luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratios. These results highlight the need for region-specific healthcare interventions to address PCOS effectively.

References

Balen, A. H., Conway, G. S., Kaltsas, G., et al. (1995). Polycystic ovary syndrome: The spectrum of the disorder in 1741 patients. Human Reproduction, 10(8), 2107-2111. https://doi.org/10.1093/oxfordjournals.humrep.a135708

Diamanti-Kandarakis, E., & Dunaif, A. (2012). Insulin resistance and the polycystic ovary syndrome revisited: An update on mechanisms and implications. Endocrine Reviews, 33(6), 981-1030. https://doi.org/10.1210/er.2011-1034

Goodarzi, M. O., Dumesic, D. A., Chazenbalk, G., & Azziz, R. (2011). Polycystic ovary syndrome: Etiology, pathogenesis, and diagnosis. Nature Reviews Endocrinology, 7(4), 219-231. https://doi.org/10.1038/nrendo.2010.217

Norman, R. J., Dewailly, D., Legro, R. S., & Hickey, T. E. (2007). Polycystic ovary syndrome. The Lancet, 370(9588), 685-697. https://doi.org/10.1016/S0140-6736(07)61345-2

Teede, H. J., Misso, M. L., Costello, M. F., et al. (2018). Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reproduction, 33(9), 1602-1618.

Dzhuraev, M., & Pardaev, D. (2019). The role of insulin resistance and hyperandrogenism in the pathogenesis of PCOS in women from Uzbekistan and Central Asia. Endocrinology and Metabolism Research Journal, 17(3), 215-222.

Khamroev, U., & Allayarov, S. (2022). Endocrine and metabolic disorders among Central Asian women with polycystic ovary syndrome: Clinical findings and interventions. Journal of Central Asian Endocrinology, 11(2), 77-83.

Saryeva, A., & Sadikova, G. (2019). The epidemiology of polycystic ovary syndrome and its metabolic implications in women of Central Asia: A review of current studies and challenges. Asian Journal of Women's Health, 24(2), 123-129.

Karimova, Z., & Isakova, N. (2018). A comparative study of PCOS prevalence in urban and rural women of Uzbekistan: The role of environmental factors. Journal of Reproductive Health and Fertility, 23(4), 101-108.

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Published

2025-02-01

How to Cite

Kholmatova Gulhayo Azimovna, Razakova Shokhsanam Tulkinovna, Ibragimova Dilhumor Dilshodbekovna, & Khafizova Rufina Radikovna. (2025). POLYCYSTIC OVARY SYNDROME IN CHILDBEARING WOMEN IN ANDIJAN: A CLINICAL, BIOCHEMICAL, AND HORMONAL ASSESSMENT. IMRAS, 8(2), 39–42. Retrieved from https://journal.imras.org/index.php/sps/article/view/2052

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